1
00:00:05,208 --> 00:00:08,252
On your right.
On your right. On your right.

2
00:00:08,253 --> 00:00:13,966
Back, back, back, back, back.
Come on, buddy.

3
00:00:13,967 --> 00:00:16,344
Yeah, Dan! Yeah!

4
00:00:16,345 --> 00:00:17,905
Yea!
Yea!

5
00:00:18,138 --> 00:00:24,978
Back, back, back, back, back.
Watch the winger!

6
00:00:33,488 --> 00:00:34,328
Yeah!

7
00:00:59,057 --> 00:01:00,497
You okay?

8
00:01:01,143 --> 00:01:03,269
Dan? Dan, talk to me.

9
00:01:03,270 --> 00:01:04,710
Dan. Dan.

10
00:01:06,023 --> 00:01:08,063
Get a doctor!

11
00:01:48,443 --> 00:01:50,820
- Hey.
- Close the door.

12
00:01:50,821 --> 00:01:53,101
Close the door.

13
00:01:56,118 --> 00:01:59,287
Is Cuddy down the hall
counting to 50?

14
00:01:59,288 --> 00:02:02,207
She knows I'm in here,
in the clinic, as she commanded.

15
00:02:02,208 --> 00:02:05,502
- She just doesn't know I'm alone.
- Well, you've got a full waiting room.

16
00:02:05,503 --> 00:02:09,965
- How long do you think you can ignore them?
- I'm off at 4:00.

17
00:02:09,966 --> 00:02:12,301
You're doing this
to avoid five minutes of work?

18
00:02:12,302 --> 00:02:15,012
If I go out there, I get assigned
a kid with a runny nose.

19
00:02:15,013 --> 00:02:18,308
That's 30 seconds looking at the nose,
25 minutes talking to a worried mom...

20
00:02:18,309 --> 00:02:21,186
who won't leave until she's sure
it's not meningitis or a tumor.

21
00:02:21,187 --> 00:02:23,605
Yes. Concerned parents
can be so annoying.

22
00:02:23,606 --> 00:02:27,317
Just tell Cuddy you've got an urgent
case. You had to leave early.
That would be lying.

23
00:02:27,318 --> 00:02:32,281
And that would be wrong. But luckily
the definition of "urgent" is fungible.

24
00:02:32,282 --> 00:02:37,562
Not the definition
of "case" though.

25
00:02:38,330 --> 00:02:43,293
You have no cases?

26
00:02:43,294 --> 00:02:47,130
You've got handpicked
doctors- specialists-

27
00:02:47,131 --> 00:02:50,092
working for you,
and they're sitting on their hands?

28
00:02:50,093 --> 00:02:53,971
- Cameron's answering my mail.
- Oh, time well spent, I'm sure.

29
00:02:53,972 --> 00:02:56,056
Foreman and Chase?

30
00:02:56,057 --> 00:02:57,377
Research?

31
00:03:04,733 --> 00:03:07,527
Nine letters.
lodine deficiency in children.

32
00:03:07,528 --> 00:03:08,968
Cretinism.

33
00:03:19,082 --> 00:03:22,043
So, 4:03 p. m.,
Dr. House checks out.

34
00:03:22,044 --> 00:03:24,045
Please write that down.

35
00:03:24,046 --> 00:03:26,339
Dr. House.
Sorry. Done for the day.

36
00:03:26,340 --> 00:03:29,300
Plenty of docs here
to take care of you.
But we had an appointment.

37
00:03:29,301 --> 00:03:32,679
Nice try, but this is
a walk-in clinic, which means
there are no appointments.

38
00:03:32,680 --> 00:03:35,015
You walk in, sign the chart,
and a doctor will see you.

39
00:03:35,016 --> 00:03:39,520
Just not me.
Your letter says that we'd see you.

40
00:03:39,521 --> 00:03:44,081
Not a big letter writer.
Here.

41
00:03:44,526 --> 00:03:48,070
When did my signature get so girlie?

42
00:03:48,071 --> 00:03:50,365
- I can explain.
- See that "G"?

43
00:03:50,366 --> 00:03:52,867
See how it makes a big loop on top?

44
00:03:52,868 --> 00:03:56,288
Doesn't even look like my handwriting.
Think I have something?

45
00:03:56,289 --> 00:03:59,750
What's the differential diagnosis
for writing G's like
a junior high school girl?

46
00:03:59,751 --> 00:04:03,545
It's impossible to get to you
through normal channels.
They have called, e-mailed.

47
00:04:03,546 --> 00:04:07,550
Perseverance does not equal worthiness.
Next time you want to get my attention,
wear something fun.

48
00:04:07,551 --> 00:04:09,552
Low-rider jeans are hot.

49
00:04:09,553 --> 00:04:14,724
Sixteen-year-old male. Sudden onset
of double vision and night terrors,
with no apparent cause.

50
00:04:14,725 --> 00:04:17,227
The kid's been to
two neurologists, and he-
Night terrors?

51
00:04:17,228 --> 00:04:22,268
- As in big scary monsters?
- Yes.

52
00:04:22,900 --> 00:04:26,445
- Where are you going?
- To see the family.

53
00:04:26,446 --> 00:04:30,574
- You're going to examine a patient?
- Nine times out of 10,
there's no reason to talk to a patient.

54
00:04:30,575 --> 00:04:34,495
But night terrors in a 16-year-old
is a very good reason
to talk to this family.

55
00:04:34,496 --> 00:04:36,056
Good work.

56
00:04:39,418 --> 00:04:41,419
Margins are fine.

57
00:04:41,420 --> 00:04:43,100
No lesions.

58
00:04:44,590 --> 00:04:46,750
Color is good.

59
00:04:46,926 --> 00:04:50,345
How long have you been
having night terrors?
Three weeks.

60
00:04:50,346 --> 00:04:55,601
He's afraid to go to bed.
He's exhausted,
can barely function.

61
00:04:55,602 --> 00:04:59,188
- What does that tell you?
- Nothing. It's just fun
watching him blink.

62
00:04:59,189 --> 00:05:09,149
Name as many animals as you can
that begin with the letter "B". Go.

63
00:05:09,450 --> 00:05:13,620
- Baby elephant?
- Baby elephant is actually
a good answer.

64
00:05:13,621 --> 00:05:16,206
- "B" is a bear of a letter.
- What does that tell you?

65
00:05:16,207 --> 00:05:20,294
Proves two things:
no neurological damage, and your son
is never gonna be chief fry cook.

66
00:05:20,295 --> 00:05:24,132
In teens, there are two
likely causes of night terrors.

67
00:05:24,133 --> 00:05:27,886
- Posttraumatic stress. Any recent
shoot-outs at your high school?
- No.

68
00:05:27,887 --> 00:05:29,179
- Then, Dave-
- Dan.

69
00:05:29,180 --> 00:05:35,978
If there's no trauma,
the other cause is... sexual abuse.

70
00:05:35,979 --> 00:05:39,481
So who's molesting you?
Teacher?

71
00:05:39,482 --> 00:05:42,526
Extra-friendly neighbor?
I'd ask if either of you
were involved, but you'd deny it.

72
00:05:42,527 --> 00:05:44,320
We would never hurt Dan.

73
00:05:44,321 --> 00:05:46,823
I say it here,
it comes out there.

74
00:05:46,824 --> 00:05:49,367
This lack of response
is consistent with abuse.

75
00:05:49,368 --> 00:05:52,245
There's no one, okay?
I- I swear.

76
00:05:52,246 --> 00:05:57,167
There was trauma.
I got hit in the head
during a lacrosse game.

77
00:05:57,168 --> 00:06:00,629
Did you know
that he got hit in the head?

78
00:06:00,630 --> 00:06:07,053
- They didn't mention it. No.
- Yeah. Why bother?

79
00:06:07,054 --> 00:06:09,680
No, no. We took him
to the E.R. after the game.

80
00:06:09,681 --> 00:06:12,267
He was scanned. They tested him.
They said he was fine.

81
00:06:12,268 --> 00:06:14,269
No concussion.
It's gotta be something else.

82
00:06:14,270 --> 00:06:17,856
You hound me for my opinion,
and then you question my diagnosis.

83
00:06:17,857 --> 00:06:21,318
Cool. E.R. obviously screwed up.
Kid's got a concussion.

84
00:06:21,319 --> 00:06:24,530
I had double vision before I was hit.
Well, that changes everything.

85
00:06:24,531 --> 00:06:27,366
You need glasses.
That's why you had double vision,

86
00:06:27,367 --> 00:06:32,163
which is why you got hit,
which is why you have a concussion,
which is why you have night terrors.

87
00:06:32,164 --> 00:06:35,249
You need to see an ophthalmologist,
which I am not.

88
00:06:35,250 --> 00:06:40,714
You enjoyed that. I brought a reasonable
case to your attention, and you shoved it
in my face just to humiliate me.

89
00:06:40,715 --> 00:06:43,633
You're an only child, aren't you?
Why would you say that?

90
00:06:43,634 --> 00:06:46,512
Because everything is about you.

91
00:06:46,513 --> 00:06:50,891
This may seem incredibly controversial,
but I think sexual abuse is bad.

92
00:06:50,892 --> 00:06:53,936
I just wanted to make sure
he wasn't being diddled
by Daddy- or Mommy.

93
00:06:53,937 --> 00:06:58,377
Anything else is just a bonus.

94
00:07:06,909 --> 00:07:10,287
I'm not an only child.
Interesting.

95
00:07:10,288 --> 00:07:13,048
What?
Don't move.

96
00:07:13,333 --> 00:07:17,336
- Did I bore you in there?
- What? Uh, no. Not- Not really.

97
00:07:17,337 --> 00:07:19,497
Are you tired?

98
00:07:19,757 --> 00:07:21,924
- Sometimes.
- He never sleeps.
Of course he's tired.

99
00:07:21,925 --> 00:07:24,427
- Right now. At this moment.
Are you tired?
- No. No.

100
00:07:24,428 --> 00:07:28,056
That twitch in your leg.
Did you feel that?

101
00:07:28,057 --> 00:07:30,350
- Didn't hurt.
- His leg twitched.
I don't see what-

102
00:07:30,351 --> 00:07:34,188
It's called a myoclonic jerk.
It's very common
when you're falling asleep.

103
00:07:34,189 --> 00:07:39,610
Respiration rate falls, and the brain
sometimes interprets this as the body dying,
so it sends a pulse to wake it up.

104
00:07:39,611 --> 00:07:41,904
- So?
- So, he's not asleep.

105
00:07:41,905 --> 00:07:43,705
He's awake.

106
00:07:44,700 --> 00:07:46,260
Admit him.

107
00:07:49,705 --> 00:07:53,166
I recognize that loopy "G".

108
00:07:53,167 --> 00:07:55,252
So, what does the jerk tell us?

109
00:07:55,253 --> 00:07:57,629
Nothing good.
The brain's losing control of the body.

110
00:07:57,630 --> 00:08:01,467
Can't order the eyes to focus,
regulate sleep patterns
or control muscles.

111
00:08:01,468 --> 00:08:03,552
A movement disorder
or a degenerative brain disease.

112
00:08:03,553 --> 00:08:07,140
Either way, this kid's gonna be
picking up his diploma
in diapers and a wheelchair.

113
00:08:07,141 --> 00:08:09,183
Maybe not that bad.
Could be an infection.

114
00:08:09,184 --> 00:08:11,311
You wish.
No fever, no white count.

115
00:08:11,312 --> 00:08:16,817
Anyone think this differential diagnosis
might be compromised because
we don't have an accurate family history?

116
00:08:16,818 --> 00:08:20,988
- I took an accurate family history.
- You didn't even take an accurate family.

117
00:08:20,989 --> 00:08:23,324
- His father's not his father.
- Why would you say that?

118
00:08:23,325 --> 00:08:26,452
Thirty percent of all dads
don't realize they're raising
someone else's kid.

119
00:08:26,453 --> 00:08:29,664
False paternity's more like 10%.
That's what our moms
would like us to believe.

120
00:08:29,665 --> 00:08:32,208
Who cares?
If he got it from his parents,
they'd both be dead.

121
00:08:32,209 --> 00:08:35,170
- Can we get on with
the differential diagnosis?
- Fifty bucks says I'm right.

122
00:08:35,171 --> 00:08:37,797
- I'll take your money.
- Hit a nerve?

123
00:08:37,798 --> 00:08:41,343
- Don't worry. I'm sure the guy who
tucked you in was your daddy.
- Make it a hundred.

124
00:08:41,344 --> 00:08:45,180
What about leukoencephalopathy
in a 16-year-old?

125
00:08:45,181 --> 00:08:47,558
It doesn't necessarily
have to be that bad.

126
00:08:47,559 --> 00:08:50,686
If we exclude the night terrors,
it could be something systemic.

127
00:08:50,687 --> 00:08:53,272
- His liver, kidneys.
Something outside the brain.
- Yes.

128
00:08:53,273 --> 00:08:57,068
- Feel free to exclude any symptom
if it makes your job easier.
- Night terrors were anecdotal.

129
00:08:57,069 --> 00:09:01,865
- He could've had a bad dream.
- No. Parents said he was conscious during
and didn't remember anything afterwards.

130
00:09:01,866 --> 00:09:03,867
- That's a night terror.
- Parents said?

131
00:09:03,868 --> 00:09:06,036
That's a good point.

132
00:09:06,037 --> 00:09:09,373
Before we condemn this kid,
maybe we should entertain
Dr. Chase's skepticism.

133
00:09:09,374 --> 00:09:19,374
I want a detailed polysomnograph.
If he's having night terrors,
I want to see them.

134
00:09:36,987 --> 00:09:39,238
I usually don't move
during night terrors.

135
00:09:39,239 --> 00:09:44,077
I'm not restraining you for them.

136
00:09:44,078 --> 00:09:47,372
E.E.G. revealed abnormalities
in your brain-

137
00:09:47,373 --> 00:09:52,173
caused nerve damage in your toes.

138
00:09:56,424 --> 00:09:59,304
What are you doing?

139
00:09:59,594 --> 00:10:02,763
- Fixing it.
- Can I talk to my parents?

140
00:10:02,764 --> 00:10:04,932
Oh, they know all about this.

141
00:10:04,933 --> 00:10:09,253
I'd really like to see them.

142
00:10:15,945 --> 00:10:20,985
Please. I'd really like them here.

143
00:10:21,117 --> 00:10:23,202
This is gonna hurt, Dan.

144
00:10:23,203 --> 00:10:25,123
Oh. Oh, God.

145
00:10:42,015 --> 00:10:45,375
That's a night terror.

146
00:10:54,695 --> 00:10:58,949
We did a C. T., M.R.I., C.B.C.,
CHEM-7 and chest X-ray.

147
00:10:58,950 --> 00:11:02,077
All the tests came back normal.
There's nothing to explain his symptoms.

148
00:11:02,078 --> 00:11:08,083
Okay, but let's pretend
there's something and go from there.
Who sees something on this M.R.I.?

149
00:11:08,084 --> 00:11:10,962
No lesions in the white matter.
No structural abnormalities.

150
00:11:10,963 --> 00:11:13,005
No space-occupying tumors.

151
00:11:13,006 --> 00:11:19,220
He's 16, so he should have
an absolutely pristine brain.
The smallest thing is abnormal.

152
00:11:19,221 --> 00:11:21,681
Meningeal enhancement.

153
00:11:21,682 --> 00:11:24,309
- My bet is viral meningitis.
- Excellent.

154
00:11:24,310 --> 00:11:26,311
Do you see what he did there?

155
00:11:26,312 --> 00:11:30,149
Took a small clue that
there's a neurological problem
and wasn't afraid to run with it.

156
00:11:30,150 --> 00:11:32,693
There's no evidence
of meningitis on that M.R.I.

157
00:11:32,694 --> 00:11:34,654
No, there's not.
He's completely wrong.

158
00:11:34,655 --> 00:11:36,739
Then what clue
are you talking about?

159
00:11:36,740 --> 00:11:41,619
He knew that I saw something
on the M.R.I., so he figured there must be
something there and took a guess.

160
00:11:41,620 --> 00:11:45,207
- Clever, but also pathetic.
- So what did you find?

161
00:11:45,208 --> 00:11:50,838
Take a close look at the corpus callosum.

162
00:11:50,839 --> 00:11:54,341
- Looks okay.
- Are we all looking at the same thing?

163
00:11:54,342 --> 00:11:56,886
Two hundred million
interhemispheric nerve fibers.

164
00:11:56,887 --> 00:12:01,683
The George Washington Bridge
between the left and right side
of the brain.

165
00:12:01,684 --> 00:12:03,604
It's subtle.

166
00:12:06,397 --> 00:12:08,773
There's some bowing. There.

167
00:12:08,774 --> 00:12:10,859
An upward arch.
Are you guessing?

168
00:12:10,860 --> 00:12:11,580
Yes.

169
00:12:12,820 --> 00:12:16,657
- Too bad. You're right.
- He probably just moved.

170
00:12:16,658 --> 00:12:19,326
Nobody stays perfectly still
for the entire M.R.I.

171
00:12:19,327 --> 00:12:24,916
Yeah. Probably got restless
and shifted one hemisphere of his brain
to a more comfortable position.

172
00:12:24,917 --> 00:12:28,253
Something is pushing on it.
If there was bowing,
could be a tumor.

173
00:12:28,254 --> 00:12:31,756
Do you see a tumor
on this M.R.I.?
No, but I don't see any bowing either.

174
00:12:31,757 --> 00:12:35,385
There's no tumor.
Just a blockage causing pressure
causing symptoms.

175
00:12:35,386 --> 00:12:38,889
Today, night terrors.
Tomorrow, he's bleeding
out of his eyes.

176
00:12:38,890 --> 00:12:48,890
Get him a radionucleotide cisternogram.
I guarantee you'll see a blockage.

177
00:12:49,568 --> 00:12:50,408
Okay.

178
00:12:54,407 --> 00:12:55,247
Easy.

179
00:12:56,200 --> 00:12:59,440
Okay. Squeeze my hand.

180
00:13:02,290 --> 00:13:05,770
All right. Squeeze hard.

181
00:13:06,962 --> 00:13:08,522
All right.

182
00:13:15,096 --> 00:13:18,431
Now I'm injecting a material
that's tagged with a radioisotope.

183
00:13:18,432 --> 00:13:22,311
It's gonna enter your spine
and travel up to your brain.

184
00:13:22,312 --> 00:13:26,315
It'll make you able to
think deep thoughts,

185
00:13:26,316 --> 00:13:29,485
run a hundred miles an hour.

186
00:13:29,486 --> 00:13:30,326
Easy.

187
00:13:44,627 --> 00:13:47,755
Their eyes aren't the same color,
but that fleck in the eyes-

188
00:13:47,756 --> 00:13:50,841
That's maybe a one-in-10 chance
if they're not related?

189
00:13:50,842 --> 00:13:53,344
No. House isn't gonna pay you
based on that.

190
00:13:53,345 --> 00:13:57,265
Any excuse we can give the folks
to justify a D.N.A. test?

191
00:13:57,266 --> 00:14:04,940
We could tell them he's got Huntington's-
whole family should be tested
or they'll all die.

192
00:14:04,941 --> 00:14:05,661
Hey.

193
00:14:06,943 --> 00:14:10,863
There's a lot of blockage.
I've scheduled him for surgery.

194
00:14:10,864 --> 00:14:14,783
We're gonna put a shunt
into one of the ventricles
to give the cerebrospinal fluid an out.

195
00:14:14,784 --> 00:14:17,495
No more pressure,
everything goes back to normal.

196
00:14:17,496 --> 00:14:23,376
He's lucky to have you
as his doctors.

197
00:14:29,133 --> 00:14:32,219
No formula. Just Mommy's
healthy, natural breast milk.

198
00:14:32,220 --> 00:14:33,180
Yummy.

199
00:14:33,972 --> 00:14:37,141
Her whole face just got
swollen like this overnight.

200
00:14:37,142 --> 00:14:38,342
Mm-hmm.

201
00:14:40,395 --> 00:14:41,835
No fever.

202
00:14:42,773 --> 00:14:45,692
Glands normal.
Missing her vaccination dates.

203
00:14:45,693 --> 00:14:48,933
We're not vaccinating.

204
00:14:49,405 --> 00:14:51,805
Gribbet! Gribbet!

205
00:14:51,991 --> 00:14:53,191
Gribbet!

206
00:14:53,576 --> 00:14:55,369
Think they don't work?

207
00:14:55,370 --> 00:14:58,747
I think some multinational
pharmaceutical company
wants me to think they work-

208
00:14:58,748 --> 00:15:02,042
pad their bottom line.
Mm-hmm.

209
00:15:02,043 --> 00:15:04,563
- May I?
- Sure.

210
00:15:05,339 --> 00:15:07,739
Gribbet. Gribbet.

211
00:15:08,092 --> 00:15:09,292
Gribbet.

212
00:15:10,427 --> 00:15:13,430
Yeah. All-natural,
no dyes is a good business.

213
00:15:13,431 --> 00:15:15,599
All-natural children's toys.

214
00:15:15,600 --> 00:15:18,185
Toy companies- they don't
arbitrarily mark up their frogs.

215
00:15:18,186 --> 00:15:21,271
They don't lie about how much
they spend on research
and development.

216
00:15:21,272 --> 00:15:26,944
The worst that a toy company
could be accused of is making
a really boring frog.

217
00:15:26,945 --> 00:15:29,864
Gribbet, gribbet, gribbet.

218
00:15:29,865 --> 00:15:32,784
You know another
really good business?

219
00:15:32,785 --> 00:15:36,287
Teeny, tiny baby coffins.

220
00:15:36,288 --> 00:15:38,623
You can get 'em
in frog green,

221
00:15:38,624 --> 00:15:41,126
fire-engine red- really.

222
00:15:41,127 --> 00:15:45,464
The antibodies in yummy Mummy
only protect the kid for six months,

223
00:15:45,465 --> 00:15:48,133
which is why these companies
think they can gouge you.

224
00:15:48,134 --> 00:15:51,929
They think that you'll spend
whatever they ask
to keep your kid alive.

225
00:15:51,930 --> 00:15:54,015
Want to change things?
Prove 'em wrong.

226
00:15:54,016 --> 00:15:58,686
Few hundred parents like you decide
they'd rather let their kid die
than cough up 40 bucks for a vaccination,

227
00:15:58,687 --> 00:16:01,273
believe me,
prices will drop really fast.

228
00:16:01,274 --> 00:16:04,276
Gribbet, gribbet, gribbet,
gribbet, gribbet.

229
00:16:04,277 --> 00:16:05,477
Gribbet.

230
00:16:05,737 --> 00:16:08,977
Tell me what she has.

231
00:16:10,700 --> 00:16:11,900
A cold.

232
00:16:13,328 --> 00:16:15,496
There's a problem.

233
00:16:15,497 --> 00:16:18,666
Complications in surgery?
Surgery went fine.
He's in recovery.

234
00:16:18,667 --> 00:16:21,085
But we took a vial
of C.S.F. and tested it.
Really?

235
00:16:21,086 --> 00:16:24,130
Turns out the bowing
wasn't the cause of his problems.
It was a symptom.

236
00:16:24,131 --> 00:16:26,299
Oligoclonal bands
and increased intrathecal IgG.

237
00:16:26,300 --> 00:16:30,512
Which means multiple sclerosis.
And the reason it takes
three of you to tell me this?

238
00:16:30,513 --> 00:16:33,349
Because we're having a disagreement
about whether or not it is M.S.

239
00:16:33,350 --> 00:16:36,977
No lesions on the M.R.I.
It's early. He's had the disease
for maybe two weeks.

240
00:16:36,978 --> 00:16:40,773
- McDonald criteria requires six months
to make a definitive diagnosis.
- Who cares about MacPhearson?

241
00:16:40,774 --> 00:16:42,775
- I hear he tortured kittens.
- McDonald.

242
00:16:42,776 --> 00:16:45,361
Oh, McDonald.
Wonderful doctor, loved kittens.

243
00:16:45,362 --> 00:16:47,364
The V.E.P. indicates slowing of the brain.

244
00:16:47,365 --> 00:16:49,407
Without the lesions,
we can't be sure.

245
00:16:49,408 --> 00:16:51,910
Well, if it is, it's gone from
zero to 60 in three weeks,

246
00:16:51,911 --> 00:16:53,954
which would indicate
rapidly progressive M.S.

247
00:16:53,955 --> 00:16:57,374
Not the fun M.S.
with the balloons and the bike rides
for cripples in wheelchairs.

248
00:16:57,375 --> 00:17:00,544
- We should wait until-
- Start treating him now,

249
00:17:00,545 --> 00:17:04,882
maybe he can walk
for another couple of years,
maybe live for another five.

250
00:17:04,883 --> 00:17:07,510
Break it to the family.
I'm going home.

251
00:17:07,511 --> 00:17:13,225
It'll take months
for a definitive diagnosis.
What'll happen to me?

252
00:17:13,226 --> 00:17:15,560
M.S. is an incredibly variable disease.

253
00:17:15,561 --> 00:17:19,064
If it is M.S., and we're not
a hundred percent sure.

254
00:17:19,065 --> 00:17:24,105
What do you think is gonna happen?

255
00:17:24,863 --> 00:17:27,240
There are some medications
to manage the symptoms,

256
00:17:27,241 --> 00:17:30,410
but as the disease progresses,
the problems will become more severe.

257
00:17:30,411 --> 00:17:32,829
Bowel and bladder dysfunction,

258
00:17:32,830 --> 00:17:35,498
loss of cognitive function, pain-

259
00:17:35,499 --> 00:17:38,499
So it's gonna hurt?

260
00:17:39,212 --> 00:17:41,713
The brain's like a big jumble of wires.

261
00:17:41,714 --> 00:17:44,341
M.S. strips them of the insulation,
and the nerves die.

262
00:17:44,342 --> 00:17:47,053
Brain interprets it as pain.

263
00:17:47,054 --> 00:17:51,307
But by starting treatment,
we're gonna prevent that
for as long as possible.

264
00:17:51,308 --> 00:17:53,309
We're looking into
a couple of specialists,

265
00:17:53,310 --> 00:18:01,950
and until we get you squared away,
you'll stay here, okay?

266
00:18:17,545 --> 00:18:20,130
Security checked the videotapes
from all perimeter cameras.

267
00:18:20,131 --> 00:18:22,424
He's still gotta be in the hospital.
Where's Chase?

268
00:18:22,425 --> 00:18:25,052
Main floor.
Okay. You take the cafeteria
and administration.

269
00:18:25,053 --> 00:18:33,573
I'll hit the research annex
and work my way back to you.

270
00:19:05,012 --> 00:19:05,732
Dan?

271
00:19:11,227 --> 00:19:15,787
I'm not here. Leave a message.

272
00:19:20,445 --> 00:19:23,322
Dr. Cuddy.
Great outfit.

273
00:19:23,323 --> 00:19:25,658
What are you doing
back here? Patient?

274
00:19:25,659 --> 00:19:32,979
No. Hooker. Went to my office
instead of my home.

275
00:19:39,549 --> 00:19:41,109
Dr. House.

276
00:19:42,052 --> 00:19:44,887
Dan's missing.
Yeah. I got that part from the message.

277
00:19:44,888 --> 00:19:48,224
You said I was needed immediately.
He shouldn't move
after a lumbar puncture.

278
00:19:48,225 --> 00:19:50,977
I agree. He's gonna have
a very nasty headache.

279
00:19:50,978 --> 00:19:54,189
That would also be my opinion
if consulted tomorrow morning.

280
00:19:54,190 --> 00:19:59,194
We wanted to keep you informed.
He heard some pretty heavy news.

281
00:19:59,195 --> 00:20:01,947
This is not a toddler wandering
around a department store.

282
00:20:01,948 --> 00:20:05,242
He's 16. You'll find him.

283
00:20:05,243 --> 00:20:07,244
I'm going home.

284
00:20:07,245 --> 00:20:10,248
So when you say,
"Call me if you need anything",
you mean don't call?

285
00:20:10,249 --> 00:20:12,583
No, I mean call me
if I could do something.

286
00:20:12,584 --> 00:20:16,755
I'm bad at search parties,
and I'm bad at sitting around
looking nervous, doing nothing.

287
00:20:16,756 --> 00:20:18,882
What about his parents?
Should we call them?

288
00:20:18,883 --> 00:20:21,343
Why? Do you think
they're hiding him?

289
00:20:21,344 --> 00:20:24,388
Make sure someone
checks the roof.

290
00:20:24,389 --> 00:20:34,389
Some of the orderlies
keep the door propped open
so they can grab a smoke.

291
00:21:02,721 --> 00:21:04,881
Dan. You okay?

292
00:21:12,315 --> 00:21:16,152
There are experimental treatments.
Ongoing research.

293
00:21:16,153 --> 00:21:18,613
Who knows what they'll discover
in a year or two.

294
00:21:18,614 --> 00:21:20,656
This is where I dropped the ball.

295
00:21:20,657 --> 00:21:25,829
Dan, we're standing
on the roof of the hospital.

296
00:21:25,830 --> 00:21:26,550
Dan.

297
00:21:27,915 --> 00:21:30,000
Dan, you're not on the field.

298
00:21:30,001 --> 00:21:32,252
He doesn't know where he is.
Dan.

299
00:21:32,253 --> 00:21:33,453
Foreman.

300
00:21:34,839 --> 00:21:35,559
Dan.

301
00:21:37,842 --> 00:21:40,482
- Dan?
- Dan, no!

302
00:21:50,439 --> 00:21:52,239
Dr. Foreman.

303
00:21:54,569 --> 00:21:56,653
I assume you found the kid.

304
00:21:56,654 --> 00:21:59,323
He almost walked off
the roof.
Suicidal?

305
00:21:59,324 --> 00:22:03,244
No, he thought he was on his
lacrosse field. Look, I was gonna
run home, shower, change-

306
00:22:03,245 --> 00:22:05,645
Conscious?
Yeah.

307
00:22:06,248 --> 00:22:08,916
How'd you talk him down?
Actually, Chase tackled him.

308
00:22:08,917 --> 00:22:10,919
How come you didn't do it?

309
00:22:10,920 --> 00:22:15,924
Right. Well, I am black,
but he was closer.

310
00:22:15,925 --> 00:22:21,085
Come on.
You can ride up with me.

311
00:22:24,601 --> 00:22:28,396
Anybody tell the family that
their boy almost stepped off a roof?
They must be thrilled.

312
00:22:28,397 --> 00:22:30,690
They're not suing,
but I think only because
Chase asked-

313
00:22:30,691 --> 00:22:33,276
Why does everybody
always think I'm being sarcastic?

314
00:22:33,277 --> 00:22:35,570
This is great news.
He doesn't have M.S.

315
00:22:35,571 --> 00:22:39,324
Parents should be thrilled.
The mom anyway. Of course,
the dad probably doesn't know-

316
00:22:39,325 --> 00:22:43,704
- Why doesn't he have M.S.?
- He was on the roof, thinking
he was on a lacrosse field.

317
00:22:43,705 --> 00:22:47,625
- Conscious, and therefore not
a night terror. You want some of this?
- Yeah, sure.

318
00:22:47,626 --> 00:22:49,794
He was in an acute
confusional state,

319
00:22:49,795 --> 00:22:52,672
which doesn't fit with
a demyelinating disease like M.S.

320
00:22:52,673 --> 00:22:54,799
Oligoclonal bands-
Were real.

321
00:22:54,800 --> 00:22:58,428
They just mean something
other than M.S.
So, what are they telling us?

322
00:22:58,429 --> 00:23:00,472
That the immune system
is working?
Right.

323
00:23:00,473 --> 00:23:02,682
He has an infection in his brain.

324
00:23:02,683 --> 00:23:04,768
What about sex?

325
00:23:04,769 --> 00:23:08,063
Well, it might get complicated.
I mean, we work together.

326
00:23:08,064 --> 00:23:11,191
- I'm older, certainly, but maybe you like that.
- I meant maybe he has neurosyphilis.

327
00:23:11,192 --> 00:23:15,029
- Huh. Nice cover.
- Sorry. R.P.R. was negative.

328
00:23:15,030 --> 00:23:18,574
We don't need
a definitive test to confirm.
Sure. Didn't need one to confirm M.S.

329
00:23:18,575 --> 00:23:23,121
Okay. Let's wait for you to
run titers on 1,400 viruses while
this kid's brain turns to mush.

330
00:23:23,122 --> 00:23:26,791
So the fact that
he doesn't have M.S.,
it's- it's really not good news after all.

331
00:23:26,792 --> 00:23:29,002
Well, it is if it's neurosyphilis.

332
00:23:29,003 --> 00:23:32,131
The likelihood of a false negative
on an R.P.R. 30%.

333
00:23:32,132 --> 00:23:35,718
Likelihood of a 16-year-old having sex:
roughly 120%.

334
00:23:35,719 --> 00:23:38,220
I'll start him on I.V. penicillin.
We're not gonna wait for that.

335
00:23:38,221 --> 00:23:41,808
The most effective way
to deliver the drug is
right into his brain via the spine.

336
00:23:41,809 --> 00:23:43,810
We can't.
In a cramped space like the brain,

337
00:23:43,811 --> 00:23:47,647
increased intracranial pressure
from a high-volume drug like penicillin
could herniate his brain stem.

338
00:23:47,648 --> 00:23:50,776
It'd kill him.
No neurologist in his right mind
would recommend that.

339
00:23:50,777 --> 00:23:53,654
Show of hands.
Who thinks I'm not
in my right mind?

340
00:23:53,655 --> 00:23:57,616
And who thinks I forget this
fairly basic neurological fact?

341
00:23:57,617 --> 00:24:01,912
Who thinks there's a third option?

342
00:24:01,913 --> 00:24:09,671
- Very good. What's the third choice?
- No idea. You just asked
if I thought there was one.

343
00:24:09,672 --> 00:24:12,841
The patient has a shunt in his brain.
There'll be no increased pressure.

344
00:24:12,842 --> 00:24:15,427
We can put as much penicillin
into his body as we want.

345
00:24:15,428 --> 00:24:21,267
Excellent. Inject him through
a lumbar puncture.

346
00:24:21,268 --> 00:24:27,190
One of us is gonna do this to you
twice a day for the next two weeks.

347
00:24:27,191 --> 00:24:30,026
- I'm ready. Go.
- He could get syphilis...

348
00:24:30,027 --> 00:24:33,696
even if he's not sexually active?

349
00:24:33,697 --> 00:24:38,118
Well, it's- it's unusual,
but it's possible.

350
00:24:38,119 --> 00:24:39,919
Okay. Relax.

351
00:24:52,885 --> 00:24:56,137
It's infected,
with a really big hole,

352
00:24:56,138 --> 00:24:58,556
like you stuck a nail in it
to relieve the pressure.

353
00:24:58,557 --> 00:25:01,643
I wouldn't do that.
Although the wound
is irregular.

354
00:25:01,644 --> 00:25:04,980
It's not cylindrical.
It's shaped like a triangle.
So, not a nail.

355
00:25:04,981 --> 00:25:07,107
- Steak knife?
- Wife's nail file.

356
00:25:07,108 --> 00:25:08,668
Nail file.

357
00:25:09,694 --> 00:25:12,822
Yeah. Pain will make you
do stupid things.

358
00:25:12,823 --> 00:25:17,994
- Something to take the edge off?
- Yeah.

359
00:25:17,995 --> 00:25:19,075
Cheers.

360
00:25:23,793 --> 00:25:26,920
So, you have family here
in Princeton?

361
00:25:26,921 --> 00:25:29,681
No.
Here on work?

362
00:25:29,716 --> 00:25:31,967
- No. Why are you-
- Does your penis hurt?

363
00:25:31,968 --> 00:25:34,220
No. What?
Should it?

364
00:25:34,221 --> 00:25:37,807
No. Just thought I'd toss you
a really inappropriate question.

365
00:25:37,808 --> 00:25:42,020
- Your lawyer's gonna love it.
- Why would I want to sue you?
I want you to treat me.

366
00:25:42,021 --> 00:25:44,564
- You're from Maplewood,
New Jersey, right?
- Yeah.

367
00:25:44,565 --> 00:25:46,900
Now, why would you
drive 70 miles...

368
00:25:46,901 --> 00:25:51,363
to get treatment for a condition
that a nine-year-old could diagnose?

369
00:25:51,364 --> 00:25:54,366
It's the free-flowing pus
that's the tip-off.

370
00:25:54,367 --> 00:25:57,328
I was in town.
Not for family.
Not for work.

371
00:25:57,329 --> 00:26:00,748
You drove 70 miles
to a walk-in clinic.
You passed two hospitals on the road.

372
00:26:00,749 --> 00:26:04,294
Either you've got a problem
with those hospitals,
or they have a problem with you.

373
00:26:04,295 --> 00:26:06,921
My guess is you've sued
half the doctors in Maplewood,

374
00:26:06,922 --> 00:26:09,049
and the rest are now
refusing to help you.

375
00:26:09,050 --> 00:26:12,844
It's ironic, isn't it?
Sort of like the boy who sued wolf.

376
00:26:12,845 --> 00:26:16,140
You know, I bet we have
a doctor here named Wolf.

377
00:26:16,141 --> 00:26:18,642
How perfect would that be?

378
00:26:18,643 --> 00:26:21,020
- I'm gonna page him.
- Okay. You know what?
Thank you.

379
00:26:21,021 --> 00:26:23,356
I'm gonna find a doctor
to take care of this.

380
00:26:23,357 --> 00:26:25,358
I didn't say I wouldn't treat you.

381
00:26:25,359 --> 00:26:28,778
- We'll drain your knee,
run some lab work. Fix you up.
- Why would you do that?

382
00:26:28,779 --> 00:26:30,780
I'm a people person.

383
00:26:30,781 --> 00:26:33,366
You actually treated him?

384
00:26:33,367 --> 00:26:35,410
All I know is he sued some doctors.

385
00:26:35,411 --> 00:26:37,829
Who am I to assume they didn't
have it coming to them?

386
00:26:37,830 --> 00:26:41,208
The cutest little tennis outfit.
My God, I thought I was
gonna have a heart attack.

387
00:26:41,209 --> 00:26:44,503
Oh, my. Didn't see you there.
That is so embarrassing.
How's your hooker doing?

388
00:26:44,504 --> 00:26:46,505
Sweet of you to ask.
Funny story.

389
00:26:46,506 --> 00:26:50,385
She was gonna be hospital
administrator, but just hated
having to screw people like that.

390
00:26:50,386 --> 00:26:53,263
- Heard you found her on the roof.
- You have very acute hearing.

391
00:26:53,264 --> 00:26:55,015
You notify the parents?

392
00:26:55,016 --> 00:26:57,017
In due course, of course.

393
00:26:57,018 --> 00:27:00,604
And is there a paternity bet
on the father of the patient?

394
00:27:00,605 --> 00:27:03,982
Doesn't sound like me.
Well, it does, actually,
but doesn't mean you're guilty.

395
00:27:03,983 --> 00:27:06,026
You think?
I saw the parents in the lobby.

396
00:27:06,027 --> 00:27:11,157
- Smart money's obviously on the father.
- My guy knows a guy who can
get you in for 50 bucks.

397
00:27:11,158 --> 00:27:15,119
Fine. Tell your guy, if I win,
you attend the faculty symposium,
and you wear a tie.

398
00:27:15,120 --> 00:27:17,664
And if I win,
no clinic hours for a week.

399
00:27:17,665 --> 00:27:21,625
My guy will call your guy.

400
00:27:22,503 --> 00:27:26,703
She's very good at her job.

401
00:27:28,051 --> 00:27:31,512
The treatments should
start helping soon.

402
00:27:31,513 --> 00:27:36,893
Let us know if it gets easier
to focus on things,
remember stuff.

403
00:27:36,894 --> 00:27:40,397
Hey, Dan. Isn't Dr. Cameron's
necklace a beauty?

404
00:27:40,398 --> 00:27:42,565
Something South American, I think.

405
00:27:42,566 --> 00:27:44,966
Yeah. Guatemalan.

406
00:27:45,570 --> 00:27:48,810
It's a cool necklace.

407
00:27:49,365 --> 00:27:53,619
- Thank you so much.
- The kid's in pain.

408
00:27:53,620 --> 00:27:56,247
Don't fight it. Just let it happen.
No.

409
00:27:56,248 --> 00:27:58,374
You'll be dead in two days.
No what?

410
00:27:58,375 --> 00:28:00,710
I give it a day.
Dan? You okay?

411
00:28:00,711 --> 00:28:01,431
Dan?

412
00:28:01,921 --> 00:28:04,464
Night terrors.
- Decomposition once he's in the grave.

413
00:28:04,465 --> 00:28:07,425
- Say good-bye to
your mother and father.
- He's hearing voices.

414
00:28:07,426 --> 00:28:11,138
You're dying.
It's all over, Dan.

415
00:28:11,139 --> 00:28:15,099
You're dying.
Dying. Dead!

416
00:28:15,393 --> 00:28:18,521
Push two milligrams
I.V. Ativan, stat.

417
00:28:18,522 --> 00:28:21,232
It's all over.
- Come on, Dan.

418
00:28:21,233 --> 00:28:24,233
Get out of my head!

419
00:28:24,862 --> 00:28:27,947
Auditory hallucination shows
further brain degeneration.

420
00:28:27,948 --> 00:28:32,035
Penicillin's not working.
So either it's
a bad batch of penicillin,

421
00:28:32,036 --> 00:28:35,873
or our diagnosis is wrong.

422
00:28:35,874 --> 00:28:37,554
Square one.

423
00:28:37,959 --> 00:28:41,962
Midnite.
L.F. T.'s, B.U.N. and creatinine are all normal.

424
00:28:41,963 --> 00:28:44,465
- Diabetes is out, and no gap.
- There goes metabolic.

425
00:28:44,466 --> 00:28:47,218
- M.R.A. rules out vasculitis.
- "I" for inflammation.

426
00:28:47,219 --> 00:28:49,929
- Too young for anything
degenerative.
- "D", see ya.

427
00:28:49,930 --> 00:28:53,266
"N" for neoplastic.
M.R.I. was clean.

428
00:28:53,267 --> 00:28:55,977
- "I" for inflammation.
- We already did that.

429
00:28:55,978 --> 00:28:59,314
- Stupid to have two I's in one mnemonic.
What's the other one?
- Infection.

430
00:28:59,315 --> 00:29:03,486
- Oligoclonal bands still have to mean something.
- But no fevers. White count's elevated,
but within range.

431
00:29:03,487 --> 00:29:06,155
We've tested for anything remotely
possible. Everything's negative.

432
00:29:06,156 --> 00:29:13,836
- C.T. scan rules out subdural.
- Trauma. Later much.

433
00:29:15,166 --> 00:29:20,295
You know the problem?
"Midnight" is actually spelled
with a "G" and an "H".

434
00:29:20,296 --> 00:29:27,344
If we could just figure out
what those letters stand for.

435
00:29:27,345 --> 00:29:32,025
It's a sick brain,
having fun,

436
00:29:32,434 --> 00:29:36,754
torturing him, talking to him.

437
00:29:40,151 --> 00:29:44,351
Scaring the hell out of him.

438
00:29:44,614 --> 00:29:49,451
Get him an E.E.G., left and right E.O.G.,
esophageal microphones.

439
00:29:49,452 --> 00:29:55,041
If this thing wants to talk,
let's listen.

440
00:29:55,042 --> 00:29:59,045
We're missing something.
This is screwed-up.

441
00:29:59,046 --> 00:30:02,632
That's why you came up with
the brain talking to the virus thing?

442
00:30:02,633 --> 00:30:04,509
I panicked, okay?

443
00:30:04,510 --> 00:30:09,790
Sounded cool though.
They bought it.

444
00:30:10,892 --> 00:30:12,332
Oh, crap.

445
00:30:13,687 --> 00:30:18,274
Another reason I don't like
meeting patients. If they don't know
what you look like, they can't yell at you.

446
00:30:18,275 --> 00:30:20,075
Here we go.

447
00:30:23,489 --> 00:30:27,367
How can you just sit there?

448
00:30:27,368 --> 00:30:29,411
If I eat standing up, I spill.

449
00:30:29,412 --> 00:30:33,624
Our son is dying,
and you could care less.

450
00:30:33,625 --> 00:30:37,670
We're going through hell.
You're doing nothing?

451
00:30:37,671 --> 00:30:42,550
- I'm sorry. You need to vent.
I understand.
- Don't be condescending.

452
00:30:42,551 --> 00:30:45,011
You haven't checked
in on him once.

453
00:30:45,012 --> 00:30:47,764
Blood pressure is 110 over 70.

454
00:30:47,765 --> 00:30:50,600
His shunt is patent, well-placed
in the right lateral ventricle.

455
00:30:50,601 --> 00:30:55,230
The E.K.G. shows a normal Q.R.S.
with deep-wave inversions throughout
both limb and precordial leads.

456
00:30:55,231 --> 00:30:58,192
L.F. T.'s are elevated,
but only twice the normal range.

457
00:30:58,193 --> 00:31:03,233
Oh, yeah. And he's hearing voices.

458
00:31:04,908 --> 00:31:07,548
Go hold his hand.

459
00:31:08,787 --> 00:31:12,867
Go on. I'll bus your tray.

460
00:31:25,347 --> 00:31:28,307
- Got any sample bags on you?
- I don't believe you.

461
00:31:28,308 --> 00:31:32,061
You're gonna run D.N.A. tests?
Their son is deathly ill.

462
00:31:32,062 --> 00:31:36,274
I know. It's terrible.
But the fact is, if I don't keep busy
with trivial things like this,

463
00:31:36,275 --> 00:31:38,485
I'm afraid
I might start to cry.
You're an ass.

464
00:31:38,486 --> 00:31:43,406
Yeah? You want to double the bet?

465
00:31:52,084 --> 00:31:54,836
General Hospital is on channel 6.

466
00:31:54,837 --> 00:31:58,465
Dan's brain's not showing
channel 6 right now.
Only mush.

467
00:31:58,466 --> 00:32:01,946
No epileptiform activity.

468
00:32:02,345 --> 00:32:05,180
What are you doing?
Waiting for C.B.C. and CHEM-7.

469
00:32:05,181 --> 00:32:09,261
Good. Run D.N.A. on these.

470
00:32:09,644 --> 00:32:14,190
What's this?
Parents' coffee cups.

471
00:32:14,191 --> 00:32:16,692
I can't believe you.
I've had this conversation
once already.

472
00:32:16,693 --> 00:32:26,053
If you've got
something else to do, do it.
Otherwise, do this.

473
00:32:27,538 --> 00:32:30,666
Dr. House.
Hey. Mr. Funsten.

474
00:32:30,667 --> 00:32:33,794
I was wondering
when you'd be back.
You got some papers for me?

475
00:32:33,795 --> 00:32:38,257
You've caused me
considerable mental distress.
I certainly hope so.

476
00:32:38,258 --> 00:32:42,387
What? Too cheap to get
your lawyer to serve it for you,
or is it just more fun this way?

477
00:32:42,388 --> 00:32:44,681
I'm obviously prepared
to consider a settlement.

478
00:32:44,682 --> 00:32:47,442
You have gonorrhea.

479
00:32:48,561 --> 00:32:52,481
No, I don't.
Well, maybe you're right,
but I have the lab result says you do.

480
00:32:52,482 --> 00:32:55,150
Could be a false positive,
and normally I'd run a second test,

481
00:32:55,151 --> 00:32:58,612
but since you're here,
I'll just go with the first.
You're just trying to scare me.

482
00:32:58,613 --> 00:33:02,033
It's reportable, you know.
Public health issue.
I'll be sure to let my wife know.

483
00:33:02,034 --> 00:33:04,744
Don't bother yourself.
The state will call for you.

484
00:33:04,745 --> 00:33:07,372
If you're clean, I'm sure
it'll all blow over. No big deal.

485
00:33:07,373 --> 00:33:12,669
There's an easy way to find out.
Get one of your doctors to run a test.

486
00:33:12,670 --> 00:33:13,750
Uh-uh.

487
00:33:14,672 --> 00:33:21,152
These are mine now.
I'll see you in court.

488
00:33:21,888 --> 00:33:25,808
West Nile negative. Not surprising
since not too many mosquitoes passing
through Jersey in December.

489
00:33:25,809 --> 00:33:28,394
No eastern equine encephalitis.
You guys aren't gonna believe this.

490
00:33:28,395 --> 00:33:32,399
What's that?
House is right.
The father's not the father.

491
00:33:32,400 --> 00:33:35,760
Dude doubled up on me.

492
00:33:36,362 --> 00:33:38,488
You're not gonna believe this.

493
00:33:38,489 --> 00:33:42,284
The mother's not the mother either.

494
00:33:42,285 --> 00:33:45,371
It's not a good idea
to move your son in his condition.

495
00:33:45,372 --> 00:33:48,791
- We just want a second opinion.
We need an answer.

496
00:33:48,792 --> 00:33:52,295
You idiots.
You lied to me.

497
00:33:52,296 --> 00:33:54,297
We didn't lie about anything.

498
00:33:54,298 --> 00:33:57,592
- You, on the other hand,
accused us of molesting our son.
- Perfect.

499
00:33:57,593 --> 00:34:00,429
Can we get off my screwups
and focus on theirs?

500
00:34:00,430 --> 00:34:02,598
Theirs is bigger.
You're not Dan's parents.

501
00:34:02,599 --> 00:34:05,476
We're his parents.
He was adopted.
He doesn't need to know.

502
00:34:05,477 --> 00:34:07,561
- I do.
- Adoption makes us just as much-

503
00:34:07,562 --> 00:34:11,983
Listen. When we were taking
his medical history, were you confused?

504
00:34:11,984 --> 00:34:14,819
Did you think we were looking for
a genetic clue to his condition,

505
00:34:14,820 --> 00:34:18,990
or did you think we were trying to
ascertain who loves him the most
in the whole wide world?

506
00:34:18,991 --> 00:34:21,201
How did you find out about this?

507
00:34:21,202 --> 00:34:24,663
- I sampled their D.N.A.
- We didn't give you any D.N.A.

508
00:34:24,664 --> 00:34:27,166
Your coffee cups from the cafeteria.

509
00:34:27,167 --> 00:34:31,170
- You can't do that.
- Again, why are we getting
hung up on what I did?

510
00:34:31,171 --> 00:34:37,093
- Your medical history is useless.
- No. We gave you a detailed history
of his biological mother.

511
00:34:37,094 --> 00:34:40,346
Her history.
Nonsmoker, good health,

512
00:34:40,347 --> 00:34:42,932
low cholesterol,
no blood pressure problems.

513
00:34:42,933 --> 00:34:45,143
Dan was adopted two weeks
after he was born.

514
00:34:45,144 --> 00:34:49,523
- You have his history. There's nothing
you need to know that we didn't tell you.
- Sounds reasonable.

515
00:34:49,524 --> 00:34:52,693
Well, if you want to transfer
your boy, that is your choice.

516
00:34:52,694 --> 00:34:57,490
I still think it's the wrong-
Was she vaccinated?

517
00:34:57,491 --> 00:35:00,535
The biological mother.
When she was a baby,
did she get her vaccinations?

518
00:35:00,536 --> 00:35:03,580
Dan was vaccinated.
At six months.

519
00:35:03,581 --> 00:35:07,375
Mm-hmm.
Do you know why kids
get vaccinated at six months?

520
00:35:07,376 --> 00:35:10,045
Because before that
they are protected...

521
00:35:10,046 --> 00:35:12,714
by their biological mother's
immune system.

522
00:35:12,715 --> 00:35:16,075
So, was she vaccinated?

523
00:35:19,264 --> 00:35:22,099
An infant picks up
a regular old measles virus.

524
00:35:22,100 --> 00:35:24,020
Gets a rash.

525
00:35:24,103 --> 00:35:27,814
He's extremely uncomfortable,
has a wicked fever, but he lives.

526
00:35:27,815 --> 00:35:31,735
Here's the kicker.
Once every million or so times,

527
00:35:31,736 --> 00:35:34,112
the virus mutates.

528
00:35:34,113 --> 00:35:36,740
Instead of Dan having
a fever and a rash,

529
00:35:36,741 --> 00:35:39,451
the virus travels
to his brain and hides,

530
00:35:39,452 --> 00:35:41,454
like a time bomb.

531
00:35:41,455 --> 00:35:43,914
In this case, for 16 years.

532
00:35:43,915 --> 00:35:47,877
Subacute sclerosing panencephalitis.

533
00:35:47,878 --> 00:35:51,423
I know. There's only been
20 cases in the United States
in the last 30 years.

534
00:35:51,424 --> 00:35:54,801
I suppose you could make
an argument the kid's still in stage I.

535
00:35:54,802 --> 00:35:57,012
Once S.S.P.E. moves
to stage II, it's-

536
00:35:57,013 --> 00:36:00,224
Boom. Stage II is universally fatal.

537
00:36:00,225 --> 00:36:03,269
I assume its impossible to know
when he might move into stage II.

538
00:36:03,270 --> 00:36:07,523
He's already started showing symptoms.
Could be a month. Could be tonight.

539
00:36:07,524 --> 00:36:09,817
Can we treat it?
Ask the neurologist.

540
00:36:09,818 --> 00:36:11,986
Intraventricular interferon.

541
00:36:11,987 --> 00:36:15,949
Not gonna shove a spike
into his brain and drip interferon
without confirming this diagnosis.

542
00:36:15,950 --> 00:36:19,786
- Tap him.
- We won't get a reliable result
for measles antibodies in his C.S.F.

543
00:36:19,787 --> 00:36:21,788
Not after everything
we've given him.

544
00:36:21,789 --> 00:36:24,625
So the wrong treatment kills
any hope of the right diagnosis.

545
00:36:24,626 --> 00:36:27,461
Why do people lie to me?

546
00:36:27,462 --> 00:36:29,463
Could also kill him.

547
00:36:29,464 --> 00:36:35,470
Your ball, Foreman.
Tell me I don't have to
biopsy his brain.

548
00:36:35,471 --> 00:36:39,140
Well, there is one other way.

549
00:36:39,141 --> 00:36:41,226
You sure this isn't gonna hurt?

550
00:36:41,227 --> 00:36:43,311
Yeah. It's just scary as hell.

551
00:36:43,312 --> 00:36:45,480
See, we go through the pupil.

552
00:36:45,481 --> 00:36:47,816
But you won't feel it.
The eye's been paralyzed.

553
00:36:47,817 --> 00:36:50,194
The needle travels
to the back of the eye,

554
00:36:50,195 --> 00:36:58,355
which is where we'll perform
the biopsy on your retina.

555
00:36:58,412 --> 00:37:01,498
So we've confirmed that
the problem is this mutated virus.

556
00:37:01,499 --> 00:37:05,377
The treatment for S.S.P.E.
is intraventricular interferon.

557
00:37:05,378 --> 00:37:08,171
We implant an ommaya reservoir
under the scalp,

558
00:37:08,172 --> 00:37:10,507
which is connected to
a ventricular catheter...

559
00:37:10,508 --> 00:37:13,135
that delivers the antiviral
directly to the left hemisphere.

560
00:37:13,136 --> 00:37:17,014
You want us to consent to this?
I don't even understand
what you're talking about.

561
00:37:17,015 --> 00:37:20,015
Well, the antiviral-

562
00:37:21,854 --> 00:37:23,855
Look. I'm sorry.

563
00:37:23,856 --> 00:37:28,318
I can explain this as best I can,
but the notion that you're gonna fully
understand your son's treatment...

564
00:37:28,319 --> 00:37:34,199
and make an informed decision
is- is kind of insane.

565
00:37:34,200 --> 00:37:37,453
Here's what you need to know.

566
00:37:37,454 --> 00:37:39,497
It's dangerous.

567
00:37:39,498 --> 00:37:41,791
It could kill him.

568
00:37:41,792 --> 00:37:44,432
You should do it.

569
00:37:54,889 --> 00:37:58,969
Did you need something else?

570
00:38:15,745 --> 00:38:18,914
You can't order a $3,200
D.N.A. test to win a bet.

571
00:38:18,915 --> 00:38:21,166
It's not an actual cost.

572
00:38:21,167 --> 00:38:25,087
I don't know if you know this,
but the hospital actually owns
the sequencing machine.

573
00:38:25,088 --> 00:38:27,757
- I'm serious.
- Tell the parents to submit
the bill to insurance.

574
00:38:27,758 --> 00:38:29,675
Insurance is not gonna
pay for a bet.

575
00:38:29,676 --> 00:38:34,097
Should. We don't make that bet,
the kid dies.

576
00:38:34,098 --> 00:38:37,058
If not for the paternity bet,
I never would have taken their D.N.A.

577
00:38:37,059 --> 00:38:41,939
Without their D.N.A., we never would have
discovered that Dan was adopted,
which was the key to this case.

578
00:38:41,940 --> 00:38:43,941
You just don't want to pay your end.

579
00:38:43,942 --> 00:38:46,944
Big mistake. My guy knows a guy.

580
00:38:46,945 --> 00:38:50,698
Fine. I will let you out of
clinic duty for one week,

581
00:38:50,699 --> 00:38:57,659
after you pay the 3,200
for the P.C.R. test.

582
00:39:01,460 --> 00:39:02,180
Ooh.

583
00:39:03,087 --> 00:39:07,633
Well, now, there's
the hundred you owe me.

584
00:39:07,634 --> 00:39:09,635
Here's a hundred
I won from Cameron.

585
00:39:09,636 --> 00:39:13,556
200 I took off of Foreman.

586
00:39:13,557 --> 00:39:15,117
And 600...

587
00:39:16,101 --> 00:39:18,861
I got from Wilson.

588
00:39:19,813 --> 00:39:21,613
Very bitter.

589
00:39:25,319 --> 00:39:27,404
Hey. Good morning.

590
00:39:27,405 --> 00:39:30,240
Good news on your E.E.G.
Treatment is working.

591
00:39:30,241 --> 00:39:32,409
And your immune system is responding.

592
00:39:32,410 --> 00:39:37,164
I know it's early,
but I just want to take a look.

593
00:39:37,165 --> 00:39:41,127
All right.
Let's see what that brain
of yours can do.

594
00:39:41,128 --> 00:39:44,672
Name as many animals as you can
that start with the letter "O".

595
00:39:44,673 --> 00:39:45,873
Ostrich.

596
00:39:47,510 --> 00:39:50,030
Ox. Old elephant.

597
00:39:50,346 --> 00:39:54,224
Well, that's two better
than last time.

598
00:39:54,225 --> 00:39:56,852
How you doing with
the whole adoption thing?

599
00:39:56,853 --> 00:39:59,689
- I knew since fifth grade.
- How's that?

600
00:39:59,690 --> 00:40:01,370
Cleft chin.

601
00:40:02,693 --> 00:40:05,361
I have one.
My dad doesn't.

602
00:40:05,362 --> 00:40:10,075
Looked it up on the Internet.
It's one of those trait things.

603
00:40:10,076 --> 00:40:13,578
That's right. It's autosomal dominant.

604
00:40:13,579 --> 00:40:19,376
Since neither of your parents have
cleft chins, it's highly unlikely
you're biologically related.

605
00:40:19,377 --> 00:40:25,049
- Are you sure you're okay?
- I've got no problems
with being adopted.

606
00:40:25,050 --> 00:40:27,810
I love my parents.

607
00:40:30,389 --> 00:40:32,891
How's he doing?
He's doing pretty well.

608
00:40:32,892 --> 00:40:34,517
He's a smart kid.

609
00:40:34,518 --> 00:40:38,718
I think he's gonna be fine.

610
00:40:40,233 --> 00:40:42,633
- Hey.
- Thanks.

611
00:41:17,940 --> 00:41:20,700
Wheels, 18. Wheels.

